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Biophysical Journal 10: 1057-1075 (1970)
© 1970 the Biophysical Society

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Simulation of Electrical Interaction of Cardiac Cells

Dennis B. Heppner and Robert Plonsey

ABSTRACT

A model of the electrical activity of excitable membrane was used to simulate action potential propagation in cardiac cells. Using an implicit method for solving finite difference equations, propagation through the intercalated disc region between two abutting cells was studied. A model of interaction was constructed and parameters of the cellular junction determined. Estimates of the intercalated disc resistance were then made from these junction parameters using a field analysis of the junction. Values of approximately 4 {Omega}-cm2 were found and correlate well with experimentally measured values.




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V. Sharma, R. C. Susil, and L. Tung
Paradoxical Loss of Excitation with High Intensity Pulses during Electric Field Stimulation of Single Cardiac Cells
Biophys. J., April 1, 2005; 88(4): 3038 - 3049.
[Abstract] [Full Text] [PDF]


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Copyright © 1970 by the Biophysical Society.