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Biophysical Journal 10: 260-268 (1970)
© 1970 the Biophysical Society

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Direct Evidence from Nuclear Magnetic Resonance Studies for Bound Sodium in Frog Skeletal Muscle

J. L. Czeisler, O. G. Fritz, Jr. and T. J. Swift

ABSTRACT

The recent work of Cope on 23Na magnetic resonance studies of frog muscle has been repeated with the view of investigating certain objections which can be raised concerning the original studies. The present work leads to the conclusion that Cope's results concerning bound sodium are essentially correct in that a large fraction of the 23Na present does not contribute normally to a detectable nuclear magnetic resonance (NMR) signal. This "missing" signal can be detected at high radio-frequency intensity however, and a signal-saturation study distinctly reveals its presence.




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W. McD. Armstrong and C. O. Lee
Sodium and Potassium Activities in Normal and "Sodium-Rich" Frog Skeletal Muscle
Science, January 29, 1971; 171(3969): 413 - 415.
[Abstract] [PDF]


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Copyright © 1970 by the Biophysical Society.