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Biophysical Journal 11: 835-848 (1971)
© 1971 the Biophysical Society
ABSTRACT
A mathematical model for the hormonal interactions of the human menstrual cycle is presented. The feedback effects of estrogen on the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are considered, including a mechanism describing the midcycle LH peak. Computer simulation with this model yields results which are periodic and in good agreement with physiological data.
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