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Biophysical Journal 15: 1095-1100 (1975)
© 1975 the Biophysical Society

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Effect of heat treatment on the elasticity of human erythrocyte membrane.

A L Rakow and R M Hochmuth

ABSTRACT

A parallel plate flow channel is employed to study the effect of heat treatment on the elasticity of human red cell membrane. An irreversible transition between 46 degrees C and 50 degrees C results in an approximately 200% increase in an elastic constant measured at 25 degrees C. This transition is attributable to irreversible protein denaturation which has been shown by other to occur at similar temperatures in calorimetric studies of red cell ghosts.




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R. Law, G. Liao, S. Harper, G. Yang, D. W. Speicher, and D. E. Discher
Pathway Shifts and Thermal Softening in Temperature-Coupled Forced Unfolding of Spectrin Domains
Biophys. J., November 1, 2003; 85(5): 3286 - 3293.
[Abstract] [Full Text] [PDF]




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Copyright © 1975 by the Biophysical Society.