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Biophysical Journal 16: 199-207 (1976)
© 1976 the Biophysical Society

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Transport calculations for light scattering in blood.

G D Pedersen, N J McCormick and L O Reynolds

ABSTRACT

In vivo measurement of the oxygen saturation levels in blood may be obtained from relative amounts of backscattered monochromatic light at two different wavelengths, as measured with a fiber-optic catheter oximeter. Because of the short mean free path length of light in blood, the backscattering can be well approximated by a previously-derived, one-wavelength transport theory solution for the half-space searchlight problem. This solution, unlike simple diffusion approximations has the advantage that the boundary condition describing illumination of a localized area of blood by a monodirectional light beam can be rigorously satisfied. Sample calculations using the solution are compared with experimental values of the reflectance of blood.






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Copyright © 1976 by the Biophysical Society.