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Biophysical Journal 19: 265-273 (1977)
© 1977 the Biophysical Society

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Determination by photon correlation spectroscopy of particle size distributions in lipid vesicle suspensions.

J H Goll and G B Stock

ABSTRACT

A method of determining particle size distributions in lipid vesicle preparations is outlined. A vesicle suspension is modeled as a polydisperse mixture of spherical shells. The distribution of particle sizes in this mixture is approximated by a continuous, piecewise linear function called a first-order spline. Excellent simultaneous fits to photon correlation spectroscopy data gathered at several different angles are presented. An error analysis is included to indicate the resolution of the method.






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Copyright © 1977 by the Biophysical Society.