Biophysical Journal 2: 381-393 (1962)
© 1962 the Biophysical Society

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Noble, D. Search for Related Content PubMed PubMed Citation Articles by Noble, D.

The Voltage Dependence of the Cardiac Membrane Conductance

ABSTRACT

Solutions have been computed for the point polarization of a sheet-like membrane obeying the equations used previously (Noble, 1960, 1962) to reproduce the Purkinje fiber action potential. It was found that, in spite of the gross non-linearity of the membrane current-voltage relations, the relations between total polarizing current and displacement of membrane potential at various distances from the polarizing electrode are remarkably linear. It is therefore concluded that Johnson and Tille's (1960, 1961) results showing linear polarizing current-voltage relations obtained by passing current through the membrane from a microelectrode during the plateau of the rabbit ventricular action potential do not conflict with the Hodgkin-Huxley theory of electrical activity.

This article has been cited by other articles:

				S Caveney Intercellular communication in insect development is hormonally controlled Science, January 13, 1978; 199(4325): 192 - 195. [Abstract] [PDF]

				W. G. Van der Kloot and B. Dane Conduction of the Action Potential in the Frog Ventricle Science, October 2, 1964; 146(3640): 74 - 75. [Abstract] [PDF]