Biophysical Journal 22: 413-430 (1978)
© 1978 the Biophysical Society

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Johnson, D H Search for Related Content PubMed PubMed Citation Articles by Johnson, D H

The relationship of post-stimulus time and interval histograms to the timming characteristics of spike trains.

ABSTRACT

PST (post-stimulus time) and interval histograms computed from recorded spike trains are related to an average timing characteristics of the spike train. The exact nature of this relationship varies with recording parameters, interfering signals, the histogram bin width, and the duration of the measurement interval. This work describes the conditions under which a PST histogram can serve as an unbiased estimate of the ensemble average of a spike train's intensity and an interval histogram can serve as an unbiased estimate of the probability density function of the interspike intervals. Simulation studies are used to confirm the validity of the theoretical results. As an example of an application, these results are used to analyze recordings of singleunit activity in the eight cranial nerve.

This article has been cited by other articles:

				A. M. Taberner and M. C. Liberman Response Properties of Single Auditory Nerve Fibers in the Mouse J Neurophysiol, January 1, 2005; 93(1): 557 - 569. [Abstract] [Full Text] [PDF]

				M. Zacksenhouse, D. H. Johnson, J. Williams, and C. Tsuchitani Single-Neuron Modeling of LSO Unit Responses J Neurophysiol, June 1, 1998; 79(6): 3098 - 3110. [Abstract] [Full Text] [PDF]

				N. Viemeister Auditory intensity discrimination at high frequencies in the presence of noise Science, September 16, 1983; 221(4616): 1206 - 1208. [Abstract] [PDF]