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Biophysical Journal 22: 501-506 (1978)
© 1978 the Biophysical Society

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Caffeine contracture and iodoacetate rigor in frog skeletal muscle. A comparison.

R P Schwarz, Jr, R Hsieh and W H Johnson

ABSTRACT

Frog sartorius muscle treated with 5.0 mM or greater caffeine exhibits stiffness similar to that obtained from muscle in iodoacetate rigor. The data provide quantitative evidence that suggests that caffeine at irreversible contracture-producing concentrations somehow induces a rigor or rigorlike state in skeletal muscle.






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Copyright © 1978 by the Biophysical Society.