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Biophysical Journal 27: 301-316 (1979)
© 1979 the Biophysical Society

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Do cardiac aneurysms blow out?

D K Bogen and T A McMahon

ABSTRACT

The possibility is suggested that cardiac aneurysms are formed when an infarcted region of the ventricular wall becomes elastically unstable and "blows out". The consequence of such a blowout could be a large saccular aneurysm or even cardiac rupture. We use a nonlinear stress-strain relation capable of describing both the passive and active myocardial wall to examine this possibility in terms of large-deformation membrane theory. Ventricular infarcts made of a material having physical properties like rubber would be expected to blow out, but those made of passive myocardium would not.




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Copyright © 1979 by the Biophysical Society.