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Biophysical Journal 3: 167-174 (1963)
© 1963 the Biophysical Society

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Estimation of Parameters of Rotatory Dispersion Curves of Proteins

Don Ridgeway

ABSTRACT

Estimation of the constants a, b, and {lambda}0 by means of the standard Moffitt-Yang plot is evaluated. It is found that the method is very insensitive as an estimation procedure and that large errors in b may be expected. Expressions for the maximum-likelihood estimates of the constants are derived.







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Copyright © 1963 by the Biophysical Society.