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Biophysical Journal 30: 129-136 (1980)
© 1980 the Biophysical Society

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The adsorption of nonpolar molecules into lipid bilayer membranes.

D W Gruen and D A Haydon

ABSTRACT

Thermodynamic considerations show that the adsorption of nonpolar molecules into lipid bilayer membranes should depend upon the curvature of the membranes. Estimations of the differences in adsorption of a small n-alkane between a planar phospholipid bilayer and liposomal vesicles have been attempted. For spherical multilamellar liposomes exposed to saturated solutions of alkane in water the adsorption is calculated to be 17-65% of the value for the planar bilayer, depending on the assumptions in the model.






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Copyright © 1980 by the Biophysical Society.