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Copyright © 1980 The Biophysical Society. All rights reserved.
Biophysical Journal, Volume 32, Issue 2, 851-856, 1 November 1980

doi:10.1016/S0006-3495(80)85020-X

Research Article


Electron diffraction from single crystals of DNA

K.H. Downing and R.M. Glaeser


Abstract

Crystals of DNA have been grown in a form suitable for study by electron diffraction and electron microscopy. Preliminary electron diffraction patterns of any type that have been obtained from single crystals of highly polymerized DNA. The patterns, obtained from frozen, hydrated crystals with the beam approximately parallel to the DNA strand axis, show a hexagonal geometrical arrangement with a (1,0) Bragg spacing of 23.1 A.