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Biophysical Journal 35: 771-781 (1981)
© 1981 the Biophysical Society

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Mechanics of Rouleau formation.

R Skalak, P R Zarda, K M Jan and S Chien

ABSTRACT

The formation of rouleau of red blood cells is considered from the standpoint of adhesion theory. With the use of the elastic properties of the red blood cell membrane obtained from previous work, the strain energy of the red blood cell in rouleau formation has been computed. The surface energy of adhesion for the bonding of two red blood cells is then computed from the variation of this strain energy. Computed cell shapes agree well with experiments.




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Copyright © 1981 by the Biophysical Society.