Biophysical Journal 45: 1031-1035 (1984)
© 1984 the Biophysical Society

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Gunning, R Search for Related Content PubMed PubMed Citation Articles by Gunning, R

Steady state current noise from the intrinsic gating of inward rectifier channels.

ABSTRACT

Steady-state current noise from the intrinsic gating of inward rectifier channels in the eggs of the marine polychaete Neanthes arenaceodentata was recorded under voltage clamp conditions. Lorentzian-shaped power spectra with corner frequencies near 1 Hz and zero-frequency asymptotes of 1 - 5 X 10(-23) A2/Hz were obtained for test potentials 15-45 mV positive to EK in solutions containing 10-40 mM Ko. The spectra are compatible with the predictions of a three-state kinetic model for inward rectification in which the single channel rectification is independent of voltage. The single channel conductance derived from this interpretation is 8 pS with 40 mM Ko.

This article has been cited by other articles:

				R Gunning Increased numbers of ion channels promoted by an intracellular second messenger Science, January 2, 1987; 235(4784): 80 - 82. [Abstract] [PDF]