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Biophysical Journal 6: 87-94 (1966)
© 1966 the Biophysical Society

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An Attempt to Infer the Electrophysiological Functions of Some Intracellular Structures in Cardiac Cells by an Electronic Analogue

C. E. Challice and T. A. Clark

ABSTRACT

A circuit which simulates the electrical conduction characteristics of the neuron has been modified by the addition of a feedback loop to simulate the electrical properties of some of the "specialized" tissues of the mammalian heart. It is suggested that there is similar electrical feedback in the muscle cells which is responsible for their electrical properties, and possible relationships between the feedback and observed structures are discussed.






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Copyright © 1966 by the Biophysical Society.