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Biophysical Journal 64: 735-742 (1993)
© 1993 the Biophysical Society

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Imaging viscoelasticity by force modulation with the atomic force microscope

M. Radmacher, R. W. Tillmann and H. E. Gaub

Physikdepartment Technische Universität München, 8046 Garching, Germany

ABSTRACT

Force modulation and phase sensitive detection was used to image soft surfaces with the atomic force microscope. This force modulation microscopy allows the simultaneous recording of images of the surface profile, the storage modulus, and the loss modulus of the sample. A theoretical treatment of the elastic tip-sample interaction is given. As examples, images of Langmuir-Blodgett films of a polymeric amphiphile and of a structured fatty acid are presented.




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Copyright © 1993 by the Biophysical Society.