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Biophysical Journal 66: 2159-2165 (1994)
© 1994 the Biophysical Society

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Mapping interaction forces with the atomic force microscope.

M Radmacher, J P Cleveland, M Fritz, H G Hansma and P K Hansma

Physics Department, University of California, Santa Barbara 83106.

ABSTRACT

Force curves were recorded as the sample was raster-scanned under the tip. This opens new opportunities for imaging with the atomic force microscope: several characteristics of the samples can be measured simultaneously, for example, topography, adhesion forces, elasticity, van der Waals, and electrostatic interactions. The new opportunities are illustrated by images of several characteristics of thin metal films, aggregates of lysozyme, and single molecules of DNA.




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Copyright © 1994 by the Biophysical Society.