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Biophysical Journal 7: 505-510 (1967)
© 1967 the Biophysical Society

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Statistical-Mechanical Studies of the {alpha} {rightleftarrows} ß Transformation in Keratins

II. The Tension-Length Isotherms

Carl W. David, Harvey B. Haukaas, Juris G. Kalnins and Robert Schor

ABSTRACT

In attempting to understand the yield region of the {alpha} {rightleftarrows} ß transformation in keratins (Astbury and Woods, 1933), we recently proposed a statistical-mechanical model (David and Schor, 1965) which generalized the work done by others on the helix {rightleftarrows} random coil transformation (Zimm and Bragg, 1959; Gibbs and DiMarzio, 1959) (thermal denaturation) to the case of a polypeptide under external tension (Birstein, 1962). We wish now to report the comparison of the quantitative aspects of this model to the observed tension-length isotherms (in the yield region) of Cotswold wool.






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Copyright © 1967 by the Biophysical Society.