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Biophysical Journal 7: 879-901 (1967)
© 1967 the Biophysical Society

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Tracer Diffusion and Unidirectional Fluxes

Peter F. Curran, Aubrey E. Taylor and A. K. Solomon

ABSTRACT

Available experimental data have been utilized to examine the effects of cross-coefficients on tracer diffusion and on the estimation of unidirectional fluxes from observations on tracer flow. In free solution or in a nonselective membrane, the interaction between the flows of tracer and the unlabelled substance are small at concentrations of biological interest for the nonelectrolytes urea, alanine, and ß-alanine, and for sodium and chloride ions. Under these conditions, measurement of tracer flow can be used to predict flow of the bulk substance to an accuracy of a few per cent.






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Copyright © 1967 by the Biophysical Society.