Biophysical Journal 71: 1335-1345 (1996)
© 1996 the Biophysical Society

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Keener, J P Articles by Panfilov, A V Search for Related Content PubMed PubMed Citation Articles by Keener, J P Articles by Panfilov, A V

A biophysical model for defibrillation of cardiac tissue.

Department of Mathematics, University of Utah, Salt Lake City 84112, USA. keener@math.utah.edu

ABSTRACT

We propose a new model for electrical activity of cardiac tissue that incorporates the effects of cellular microstructure. As such, this model provides insight into the mechanism of direct stimulation and defibrillation of cardiac tissue after injection of large currents. To illustrate the usefulness of the model, numerical stimulations are used to show the difference between successful and unsuccessful defibrillation of large pieces of tissue.

This article has been cited by other articles:

				N. H. L. Kuijpers, R. H. Keldermann, T. Arts, and P. A. J. Hilbers Computer simulations of successful defibrillation in decoupled and non-uniform cardiac tissue Europace, January 1, 2005; 7(s2): S166 - S177. [Abstract] [Full Text] [PDF]

				I. R. Efimov A Shocking Experience : Ionic Modulation of Virtual Electrodes in Defibrillation Circ. Res., September 15, 2000; 87(6): 429 - 430. [Full Text] [PDF]