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Biophys J, December 2000, p. 2893-2901, Vol. 79, No. 6

A Quantitative Approximation Scheme for the Traveling Wave Solutions in the Hodgkin-Huxley Model

C. B. Muratov

Department of Mathematical Sciences, New Jersey Institute of Technology, University Heights, Newark, New Jersey 07102 USA

We introduce an approximation scheme for the Hodgkin-Huxley model of nerve conductance that allows calculation of both the speed and shape of the traveling pulses, in quantitative agreement with the solutions of the model. We demonstrate that the reduced problem for the front of the traveling pulse admits a unique solution. We obtain an explicit analytical expression for the speed of the pulses that is valid with good accuracy in a wide range of the parameters.

Biophys J, December 2000, p. 2893-2901, Vol. 79, No. 6
© 2000 by the Biophysical Society   0006-3495/00/12/2893/09  $2.00




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