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Biophysical Journal 8: 1228-1235 (1968)
© 1968 the Biophysical Society

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On the Shape of the Erythrocyte

L. Lopez, I. M. Duck and W. A. Hunt

ABSTRACT

A model is postulated which attributes the distinctive biconcave shape of the human erythrocyte to a balance of forces acting on the membrane. The forces considered are electrostatic forces due to a charge distribution on the membrane, a hydrostatic pressure difference acting across the membrane, and forces arising from a constant tension in the membrane. A numerical study indicates that the postulated model will produce an equilibrium shape which is very similar to the observed shape of the human erythrocyte.






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Copyright © 1968 by the Biophysical Society.