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Glucose and Mannitol Diffusion in Human Dura Mater

Department of Optics, Saratov State University, Saratov, Russia

Correspondence: Address reprint requests to Alexey N. Bashkatov, E-mail: bash{at}optics.sgu.ru.

An in vitro experimental study of the control of the human dura mater optical properties at administration of aqueous solutions of glucose and mannitol has been presented. The significant increase of the dura mater optical transmittance under action of immersion liquids has been demonstrated. Diffusion coefficients of glucose and mannitol in the human dura mater tissue at 20°C have been estimated as (1.63 ± 0.29) x 10^-6cm²/s and as (1.31 ± 0.41) x 10^-6 cm²/s, respectively. Experiments show that administration of immersion liquids allows for the effective control of tissue optical characteristics that make dura mater more transparent, thereby increasing the ability of light penetration through the tissue.

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