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Biophysical Journal 9: 330-346 (1969)
© 1969 the Biophysical Society

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Radiation-Induced Breaks of DNA in Cultured Mammalian Cells

W. Veatch and S. Okada

ABSTRACT

Mouse leukemic cells (L5178Y) in suspension culture were irradiated and the extent of single-strand breaks and double-strand cuts of DNA was estimated by sucrose gradient centrifugation. The radiation produced 3.0 single-strand breaks per cell (G1 stage) per rad and approximately 0.3 double-strand breaks per cell (G1 stage) per rad.






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Copyright © 1969 by the Biophysical Society.