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Originally published as Biophys J. BioFAST on May 19, 2006.
doi:10.1529/biophysj.106.084434
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Biophysical Journal 91:L14-L15 (2006)
© 2006 The Biophysical Society

Probing the Double Layer: Effect of Image Forces on AFM

Frederick Sachs

Single Molecule Biophysics, State University of New York, Buffalo, New York 14214

Correspondence: Address reprint requests and inquiries to Frederick Sachs, Tel.: 716-829-3289, Ext. 105; Fax: 716-829-2465; E-mail: sachs{at}buffalo.edu.

Force probes such as AFM tips or laser trap latex beads have a dielectric constant much less than that of the water that they displace. Thus when a probe approaches a charged surface under water it will be repelled simply based upon the image forces, and these can be of nN magnitude.




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Biophys. J., January 15, 2007; 92(2): 699a - 699a.
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