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Stretching to Understand Proteins—A Survey of the Protein Data Bank

Joanna I. Sukowska and Marek Cieplak

Institute of Physics, Polish Academy of Sciences, Warsaw, Poland

Correspondence: Address reprint requests to Marek Cieplak, Tel.: 48-22-843-6601, x3365; E-mail: mc{at}ifpan.edu.pl.

We make a survey of resistance of 7510 proteins to mechanical stretching at constant speed as studied within a coarse-grained molecular dynamics model. We correlate the maximum force of resistance with the native structure, predict proteins which should be especially strong, and identify the nature of their force clamps.

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