Cover picture: The low resolution structure of pancreatic ribonuclease inhibitor directly modeled from small angle x-ray solution scattering. The figure illustrates one of the first tests of a new scattering modeling method based on Debye calculation and genetic algorithms. The solution scattering profile of this protein was calculated to a reciprocal Bragg spacing of 17 Å from the crystallographic structure (B. Kobe and J. Deisenhofer, 1993; 1bnh.pdb), shown as a yellow ribbon. The method was then used to find possible bead models which fit the scattering profile. These were all similar and reproduced the size and shape of the problem structure to the modeling resolution. One of the models (made of 147 beads of radius 4 Å) is shown by the blue transparent surface. The figure was displayed using Grasp and Raster3D programs. See the article by Chacón et al. on p. 2760.