Cover picture: Representative AFM topography images of individual nuclear pore complexes (NPCs) showing the variation in central granule location. The top left image depicts a single NPC in which the central granule is totally recessed. The middle image shows a single NPC in which the central granule is only partially recessed while the bottom right image reveals a single NPC in which the central granule fully protrudes from the central lumen. See the article by Moore-Nichols et al. on p. 1421.