NEW AND NOTABLE:

Liming Hou and Michael G. Zagorski

Sorting Out the Driving Forces for Parallel and Antiparallel Alignment in the Aß Peptide Fibril Structure
Biophys. J. 2004 86: 1-2. [Full Text] [PDF]  

BIOPHYSICAL THEORY AND MODELING:

Francesco Berti, Paolo Costantino, Marco Fragai, and Claudio Luchinat

Water Accessibility, Aggregation, and Motional Features of Polysaccharide-Protein Conjugate Vaccines
Biophys. J. 2004 86: 3-9. [Abstract] [Full Text] [PDF]  

Ivan V. Maly, H. Steven Wiley, and Douglas A. Lauffenburger

Self-Organization of Polarized Cell Signaling via Autocrine Circuits: Computational Model Analysis
Biophys. J. 2004 86: 10-22. [Abstract] [Full Text] [PDF]  

Erik Sandelin

On Hydrophobicity and Conformational Specificity in Proteins
Biophys. J. 2004 86: 23-30. [Abstract] [Full Text] [PDF]  

Hyunbum Jang, Carol K. Hall, and Yaoqi Zhou

Assembly and Kinetic Folding Pathways of a Tetrameric ß-Sheet Complex: Molecular Dynamics Simulations on Simplified Off-Lattice Protein Models
Biophys. J. 2004 86: 31-49. [Abstract] [Full Text] [PDF]  

Fangqiang Zhu, Emad Tajkhorshid, and Klaus Schulten

Theory and Simulation of Water Permeation in Aquaporin-1
Biophys. J. 2004 86: 50-57. [Abstract] [Full Text] [PDF]  

Audun Bakk, Ralf Metzler, and Kim Sneppen

Sensitivity of O_R in Phage
Biophys. J. 2004 86: 58-66. [Abstract] [Full Text] [PDF]  

Jessica M. J. Swanson, Richard H. Henchman, and J. Andrew McCammon

Revisiting Free Energy Calculations: A Theoretical Connection to MM/PBSA and Direct Calculation of the Association Free Energy
Biophys. J. 2004 86: 67-74. [Abstract] [Full Text] [PDF]  

Moisés Santillán and Michael C. Mackey

Why the Lysogenic State of Phage Is So Stable: A Mathematical Modeling Approach
Biophys. J. 2004 86: 75-84. [Abstract] [Full Text] [PDF]  

Ali Rana Atilgan, Pelin Akan, and Canan Baysal

Small-World Communication of Residues and Significance for Protein Dynamics
Biophys. J. 2004 86: 85-91. [Abstract] [Full Text] [PDF]  

Gennady V. Miloshevsky and Peter C. Jordan

Gating Gramicidin Channels in Lipid Bilayers: Reaction Coordinates and the Mechanism of Dissociation
Biophys. J. 2004 86: 92-104. [Abstract] [Full Text] [PDF]  

Xavier Deupi, Mireia Olivella, Cedric Govaerts, Juan Antonio Ballesteros, Mercedes Campillo, and Leonardo Pardo

Ser and Thr Residues Modulate the Conformation of Pro-Kinked Transmembrane -Helices
Biophys. J. 2004 86: 105-115. [Abstract] [Full Text] [PDF]  

Yinghao Wu and Jianpeng Ma

Refinement of F-Actin Model against Fiber Diffraction Data by Long-Range Normal Modes
Biophys. J. 2004 86: 116-124. [Abstract] [Full Text] [PDF]  

CHANNELS, RECEPTORS, AND TRANSPORTERS:

Marilène P. Gagnon, Pierre Bissonnette, Louis-Martin Deslandes, Bernadette Wallendorff, and Jean-Yves Lapointe

Glucose Accumulation Can Account for the Initial Water Flux Triggered by Na⁺/Glucose Cotransport
Biophys. J. 2004 86: 125-133. [Abstract] [Full Text] [PDF]  

S. Peng, N. G. Publicover, G. J. Kargacin, D. Duan, J. A. Airey, and John L. Sutko

Imaging Single Cardiac Ryanodine Receptor Ca²⁺ Fluxes in Lipid Bilayers
Biophys. J. 2004 86: 134-144. [Abstract] [Full Text] [PDF]  

S. Peng, N. G. Publicover, J. A. Airey, J. E. Hall, H. T. Haigler, D. Jiang, S. R. Wayne Chen, and J. L. Sutko

Diffusion of Single Cardiac Ryanodine Receptors in Lipid Bilayers Is Decreased by Annexin 12
Biophys. J. 2004 86: 145-151. [Abstract] [Full Text] [PDF]  

Alexander G. Komarov, Brett H. Graham, William J. Craigen, and Marco Colombini

The Physiological Properties of a Novel Family of VDAC-Like Proteins from Drosophila melanogaster
Biophys. J. 2004 86: 152-162. [Abstract] [Full Text] [PDF]  

Zoltán Cseresnyés and Martin F. Schneider

Peripheral Hot Spots for Local Ca²⁺ Release after Single Action Potentials in Sympathetic Ganglion Neurons
Biophys. J. 2004 86: 163-181. [Abstract] [Full Text] [PDF]  

Jian-Xin Shen, ShiQiang Wang, Long-Sheng Song, Taizhen Han, and Heping Cheng

Polymorphism of Ca²⁺ Sparks Evoked from In-Focus Ca²⁺ Release Units in Cardiac Myocytes
Biophys. J. 2004 86: 182-190. [Abstract] [Full Text] [PDF]  

E. Dietlind Koch, Baldomero M. Olivera, Heinrich Terlau, and Franco Conti

The Binding of -Conotoxin PVIIA and Fast C-Type Inactivation of Shaker K⁺ Channels are Mutually Exclusive
Biophys. J. 2004 86: 191-209. [Abstract] [Full Text] [PDF]  

Manuel Gebauer, Dirk Isbrandt, Kathrin Sauter, Britta Callsen, Andreas Nolting, Olaf Pongs, and Robert Bähring

N-type Inactivation Features of Kv4.2 Channel Gating
Biophys. J. 2004 86: 210-223. [Abstract] [Full Text] [PDF]  

Cristiana Picco, Monica Bregante, Alessia Naso, Paola Gavazzo, Alex Costa, Elide Formentin, Patrick Downey, Fiorella Lo Schiavo, and Franco Gambale

Histidines Are Responsible for Zinc Potentiation of the Current in KDC1 Carrot Channels
Biophys. J. 2004 86: 224-234. [Abstract] [Full Text] [PDF]  

Holger M. Becker, Stefan Bröer, and Joachim W. Deitmer

Facilitated Lactate Transport by MCT1 when Coexpressed with the Sodium Bicarbonate Cotransporter (NBC) in Xenopus Oocytes
Biophys. J. 2004 86: 235-247. [Abstract] [Full Text] [PDF]  

Parvez I. Haris, Gérard Molle, and Hervé Duclohier

Conformational Changes in Alamethicin Associated with Substitution of Its -Methylalanines with Leucines: A FTIR Spectroscopic Analysis and Correlation with Channel Kinetics
Biophys. J. 2004 86: 248-253. [Abstract] [Full Text] [PDF]  

MEMBRANES:

André Ziegler and Joachim Seelig

Interaction of the Protein Transduction Domain of HIV-1 TAT with Heparan Sulfate: Binding Mechanism and Thermodynamic Parameters
Biophys. J. 2004 86: 254-263. [Abstract] [Full Text] [PDF]  

Dieter Kurad, Gunnar Jeschke, and Derek Marsh

Lateral Ordering of Lipid Chains in Cholesterol-Containing Membranes: High-Field Spin-Label EPR
Biophys. J. 2004 86: 264-271. [Abstract] [Full Text] [PDF]  

Wai Leung Lau, David S. Ege, James D. Lear, Daniel A. Hammer, and William F. DeGrado

Oligomerization of Fusogenic Peptides Promotes Membrane Fusion by Enhancing Membrane Destabilization
Biophys. J. 2004 86: 272-284. [Abstract] [Full Text] [PDF]  

Michael Schwarzott, Peter Lasch, Dieter Baurecht, Dieter Naumann, and Urs Peter Fringeli

Electric Field-Induced Changes in Lipids Investigated by Modulated Excitation FTIR Spectroscopy
Biophys. J. 2004 86: 285-295. [Abstract] [Full Text] [PDF]  

Reiko Ishitsuka, Akiko Yamaji-Hasegawa, Asami Makino, Yoshio Hirabayashi, and Toshihide Kobayashi

A Lipid-Specific Toxin Reveals Heterogeneity of Sphingomyelin-Containing Membranes
Biophys. J. 2004 86: 296-307. [Abstract] [Full Text] [PDF]  

Antonio Cruz, Luis Vázquez, Marisela Vélez, and Jesús Pérez-Gil

Effect of Pulmonary Surfactant Protein SP-B on the Micro- and Nanostructure of Phospholipid Films
Biophys. J. 2004 86: 308-320. [Abstract] [Full Text] [PDF]  

Marco Diociaiuti, Irene Ruspantini, Cristiano Giordani, Federico Bordi, and Pietro Chistolini

Distribution of GD3 in DPPC Monolayers: A Thermodynamic and Atomic Force Microscopy Combined Study
Biophys. J. 2004 86: 321-328. [Abstract] [Full Text] [PDF]  

Kalpana Bhargava and Jimmy B. Feix

Membrane Binding, Structure, and Localization of Cecropin-Mellitin Hybrid Peptides: A Site-Directed Spin-Labeling Study
Biophys. J. 2004 86: 329-336. [Abstract] [Full Text] [PDF]  

Parag Mukhopadhyay, Hans J. Vogel, and D. Peter Tieleman

Distribution of Pentachlorophenol in Phospholipid Bilayers: A Molecular Dynamics Study
Biophys. J. 2004 86: 337-345. [Abstract] [Full Text] [PDF]  

MUSCLE AND CONTRACTILITY:

Hajime M. Sakakibara, Yuki Kunioka, Takenori Yamada, and Shinji Kamimura

Diameter Oscillation of Axonemes in Sea-Urchin Sperm Flagella
Biophys. J. 2004 86: 346-352. [Abstract] [Full Text] [PDF]  

Xiumei Liu and Gerald H. Pollack

Stepwise Sliding of Single Actin and Myosin Filaments
Biophys. J. 2004 86: 353-358. [Abstract] [Full Text] [PDF]  

Bishow B. Adhikari and Kuan Wang

Interplay of Troponin- and Myosin-Based Pathways of Calcium Activation in Skeletal and Cardiac Muscle: The Use of W7 as an Inhibitor of Thin Filament Activation
Biophys. J. 2004 86: 359-370. [Abstract] [Full Text] [PDF]  

NUCLEIC ACIDS:

Sergei Khrapunov and Michael Brenowitz

Comparison of the Effect of Water Release on the Interaction of the Saccharomyces cerevisiae TATA Binding Protein (TBP) with "TATA Box" Sequences Composed of Adenosine or Inosine
Biophys. J. 2004 86: 371-383. [Abstract] [Full Text] [PDF] [Supplemental Material]  

PHOTOBIOPHYSICS:

Andreas Schenk, Sergey Ivanchenko, Carlheinz Röcker, Jörg Wiedenmann, and G. Ulrich Nienhaus

Photodynamics of Red Fluorescent Proteins Studied by Fluorescence Correlation Spectroscopy
Biophys. J. 2004 86: 384-394. [Abstract] [Full Text] [PDF]  

PROTEINS:

Andrew N. Hoofnagle, James W. Stoner, Thomas Lee, Sandra S. Eaton, and Natalie G. Ahn

Phosphorylation-Dependent Changes in Structure and Dynamics in ERK2 Detected by SDSL and EPR
Biophys. J. 2004 86: 395-403. [Abstract] [Full Text] [PDF]  

Timothy R. Dafforn, Jacindra Rajendra, David J. Halsall, Louise C. Serpell, and Alison Rodger

Protein Fiber Linear Dichroism for Structure Determination and Kinetics in a Low-Volume, Low-Wavelength Couette Flow Cell
Biophys. J. 2004 86: 404-410. [Abstract] [Full Text] [PDF]  

R. H. Leary, J. B. Rosen, and P. Jambeck

An Optimal Structure-Discriminative Amino Acid Index for Protein Fold Recognition
Biophys. J. 2004 86: 411-419. [Abstract] [Full Text] [PDF]  

Binbin Liu, Mark Bartlam, Renjun Gao, Weihong Zhou, Hai Pang, Yiwei Liu, Yan Feng, and Zihe Rao

Crystal Structure of the Hyperthermophilic Inorganic Pyrophosphatase from the Archaeon Pyrococcus horikoshii
Biophys. J. 2004 86: 420-427. [Abstract] [Full Text] [PDF]  

David J. Gordon, John J. Balbach, Robert Tycko, and Stephen C. Meredith

Increasing the Amphiphilicity of an Amyloidogenic Peptide Changes the ß-Sheet Structure in the Fibrils from Antiparallel to Parallel
Biophys. J. 2004 86: 428-434. [Abstract] [Full Text] [PDF]  

Catherine Tetreau, Yves Blouquit, Eugene Novikov, Eric Quiniou, and Daniel Lavalette

Competition with Xenon Elicits Ligand Migration and Escape Pathways in Myoglobin
Biophys. J. 2004 86: 435-447. [Abstract] [Full Text] [PDF]  

Chiara Ciaccio, Giampiero De Sanctis, Stefano Marini, Federica Sinibaldi, Roberto Santucci, Alessandro Arcovito, Andrea Bellelli, Elena Ghibaudi, Pia Ferrari Rosa, and Massimo Coletta

Proton Linkage for CO Binding and Redox Properties of Bovine Lactoperoxidase
Biophys. J. 2004 86: 448-454. [Abstract] [Full Text] [PDF]  

H. Haas, C. L. P. Oliveira, I. L. Torriani, E. Polverini, A. Fasano, G. Carlone, P. Cavatorta, and P. Riccio

Small Angle X-Ray Scattering from Lipid-Bound Myelin Basic Protein in Solution
Biophys. J. 2004 86: 455-460. [Abstract] [Full Text] [PDF]  

Dessislava Nikolova Georgieva, Nicolay Genov, Krassimir Hristov, Karsten Dierks, and Christian Betzel

Interactions of the Neurotoxin Vipoxin in Solution Studied by Dynamic Light Scattering
Biophys. J. 2004 86: 461-466. [Abstract] [Full Text] [PDF]  

H. Lesch, J. Schlichter, J. Friedrich, and J. M. Vanderkooi

Molecular Probes: What Is the Range of Their Interaction with the Environment?
Biophys. J. 2004 86: 467-472. [Abstract] [Full Text] [PDF]  

Raghu K. Chitta and Michael L. Gross

Electrospray Ionization-Mass Spectrometry and Tandem Mass Spectrometry Reveal Self-Association and Metal-Ion Binding of Hydrophobic Peptides: A Study of the Gramicidin Dimer
Biophys. J. 2004 86: 473-479. [Abstract] [Full Text] [PDF]  

A. De Francesco, M. Marconi, S. Cinelli, G. Onori, and A. Paciaroni

Picosecond Internal Dynamics of Lysozyme as Affected by Thermal Unfolding in Nonaqueous Environment
Biophys. J. 2004 86: 480-487. [Abstract] [Full Text] [PDF]  

M. A. Miteva, J. M. Brugge, J. Rosing, G. A. F. Nicolaes, and B. O. Villoutreix

Theoretical and Experimental Study of the D2194G Mutation in the C2 Domain of Coagulation Factor V
Biophys. J. 2004 86: 488-498. [Abstract] [Full Text] [PDF]  

SUPERMOLECULAR ASSEMBLIES:

Marina Belenky, Rebecca Meyers, and Judith Herzfeld

Subunit Structure of Gas Vesicles: A MALDI-TOF Mass Spectrometry Study
Biophys. J. 2004 86: 499-505. [Abstract] [Full Text] [PDF]  

SPECTROSCOPY, IMAGING, OTHER TECHNIQUES:

Katrin G. Heinze, Michael Jahnz, and Petra Schwille

Triple-Color Coincidence Analysis: One Step Further in Following Higher Order Molecular Complex Formation
Biophys. J. 2004 86: 506-516. [Abstract] [Full Text] [PDF]  

F. Moreno-Herrero, M. Pérez, A. M. Baró, and J. Avila

Characterization by Atomic Force Microscopy of Alzheimer Paired Helical Filaments under Physiological Conditions
Biophys. J. 2004 86: 517-525. [Abstract] [Full Text] [PDF]  

Gianluca Croce, Alberto Frache, Marco Milanesio, Leonardo Marchese, Mauro Causà, Davide Viterbo, Alessia Barbaglia, Vera Bolis, Giorgio Bavestrello, Carlo Cerrano, Umberto Benatti, Marina Pozzolini, Marco Giovine, and Heinz Amenitsch

Structural Characterization of Siliceous Spicules from Marine Sponges
Biophys. J. 2004 86: 526-534. [Abstract] [Full Text] [PDF]  

Anders Fridberger, Jerker Widengren, and Jacques Boutet de Monvel

Measuring Hearing Organ Vibration Patterns with Confocal Microscopy and Optical Flow
Biophys. J. 2004 86: 535-543. [Abstract] [Full Text] [PDF] [Supplemental Material]  

CELL BIOPHYSICS:

Linda J. Rinko, Michael B. Lawrence, and William H. Guilford

The Molecular Mechanics of P- and L-Selectin Lectin Domains Binding to PSGL-1
Biophys. J. 2004 86: 544-554. [Abstract] [Full Text] [PDF]  

Sara K. Davis and Christopher J. Bardeen

The Connection between Chromatin Motion on the 100 nm Length Scale and Core Histone Dynamics in Live XTC-2 Cells and Isolated Nuclei
Biophys. J. 2004 86: 555-564. [Abstract] [Full Text] [PDF]  

Masayuki Ikeda, Shigeru Suzuki, Masahiro Kishio, Moritoshi Hirono, Takashi Sugiyama, Junko Matsuura, Teppei Suzuki, Takayuki Sota, Charles N. Allen, Shiro Konishi, and Tohru Yoshioka

Hydrogen-Deuterium Exchange Effects on ß-Endorphin Release from AtT20 Murine Pituitary Tumor Cells
Biophys. J. 2004 86: 565-575. [Abstract] [Full Text] [PDF]  

Harish Shankaran and Sriram Neelamegham

Hydrodynamic Forces Applied on Intercellular Bonds, Soluble Molecules, and Cell-Surface Receptors
Biophys. J. 2004 86: 576-588. [Abstract] [Full Text] [PDF]  

Jason M. Haugh and Ian C. Schneider

Spatial Analysis of 3' Phosphoinositide Signaling in Living Fibroblasts: I. Uniform Stimulation Model and Bounds on Dimensionless Groups
Biophys. J. 2004 86: 589-598. [Abstract] [Full Text] [PDF]  

Ian C. Schneider and Jason M. Haugh

Spatial Analysis of 3' Phosphoinositide Signaling in Living Fibroblasts: II. Parameter Estimates for Individual Cells from Experiments
Biophys. J. 2004 86: 599-608. [Abstract] [Full Text] [PDF]  

Piet H. M. Lommerse, Gerhard A. Blab, Laurent Cognet, Gregory S. Harms, B. Ewa Snaar-Jagalska, Herman P. Spaink, and Thomas Schmidt

Single-Molecule Imaging of the H-Ras Membrane-Anchor Reveals Domains in the Cytoplasmic Leaflet of the Cell Membrane
Biophys. J. 2004 86: 609-616. [Abstract] [Full Text] [PDF] [Supplemental Material]  

Adam Engler, Lucie Bacakova, Cynthia Newman, Alina Hategan, Maureen Griffin, and Dennis Discher

Substrate Compliance versus Ligand Density in Cell on Gel Responses
Biophys. J. 2004 86: 617-628. [Abstract] [Full Text] [PDF]  

BIOENERGETICS:

Frederic Joubert, Henry M. Fales, Han Wen, Christian A. Combs, and Robert S. Balaban

NADH Enzyme-Dependent Fluorescence Recovery after Photobleaching (ED-FRAP): Applications to Enzyme and Mitochondrial Reaction Kinetics, In Vitro
Biophys. J. 2004 86: 629-645. [Abstract] [Full Text] [PDF]  

ELECTROPHYSIOLOGY:

Elizabeth García-Pérez, Mariana Vargas-Caballero, Norma Velazquez-Ulloa, Antonmaria Minzoni, and Francisco F. De-Miguel

Synaptic Integration in Electrically Coupled Neurons
Biophys. J. 2004 86: 646-655. [Abstract] [Full Text] [PDF] [Supplemental Material]  

LETTERS TO THE EDITOR:

Michael Korostishevsky, Zeev Zaslavsky, and Solomon S. Stavrov

Temperature Dependence of the Iron-Histidine Resonance Raman Band of Deoxyheme Proteins: Anharmonic Coupling Versus Distribution over Taxonomic Conformational Substates
Biophys. J. 2004 86: 656-659. [Full Text] [PDF]  

Wolfgang Dreybrodt, Joachim Schott, and Reinhard Schweitzer-Stenner

Comments on the Article "Temperature Dependence of the Iron-Histidine Resonance Raman Band of Deoxyheme Proteins: Anharmonic Coupling Versus Distribution over Taxonomic Conformational Substates" by Korostishevsky et al.
Biophys. J. 2004 86: 660-661. [Full Text] [PDF]  

CORRECTIONS:

Corrections
Biophys. J. 2004 86: 662(1) [Full Text] [PDF]  

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