NEW AND NOTABLE:

Jörg Langowski

Melting under Stress
Biophys. J. 2004 86: 2639-2640. [Full Text] [PDF]  

BIOPHYSICAL THEORY AND MODELING:

Nam-Kyung Lee and D. Thirumalai

Pulling-Speed-Dependent Force-Extension Profiles for Semiflexible Chains
Biophys. J. 2004 86: 2641-2649. [Abstract] [Full Text] [PDF]  

Réka Albert, Yu-wen Chiu, and Hans G. Othmer

Dynamic Receptor Team Formation Can Explain the High Signal Transduction Gain in Escherichia coli
Biophys. J. 2004 86: 2650-2659. [Abstract] [Full Text] [PDF]  

R. Thul and M. Falcke

Release Currents of IP₃ Receptor Channel Clusters and Concentration Profiles
Biophys. J. 2004 86: 2660-2673. [Abstract] [Full Text] [PDF]  

M. R. Bennett, L. Farnell, and W. G. Gibson

The Facilitated Probability of Quantal Secretion within an Array of Calcium Channels of an Active Zone at the Amphibian Neuromuscular Junction
Biophys. J. 2004 86: 2674-2690. [Abstract] [Full Text] [PDF]  

Victor Matveev, Robert S. Zucker, and Arthur Sherman

Facilitation through Buffer Saturation: Constraints on Endogenous Buffering Properties
Biophys. J. 2004 86: 2691-2709. [Abstract] [Full Text] [PDF]  

Nicolas Fatin-Rouge, Konstantin Starchev, and Jacques Buffle

Size Effects on Diffusion Processes within Agarose Gels
Biophys. J. 2004 86: 2710-2719. [Abstract] [Full Text] [PDF]  

M. Bindschadler, E. A. Osborn, C. F. Dewey, Jr., and J. L. McGrath

A Mechanistic Model of the Actin Cycle
Biophys. J. 2004 86: 2720-2739. [Abstract] [Full Text] [PDF]  

Baochi Nguyen, Arpita Upadhyaya, Alexander van Oudenaarden, and Michael P. Brenner

Elastic Instability in Growing Yeast Colonies
Biophys. J. 2004 86: 2740-2747. [Abstract] [Full Text] [PDF]  

Karen Lai, Matthew J. Robertson, and David V. Schaffer

The Sonic Hedgehog Signaling System as a Bistable Genetic Switch
Biophys. J. 2004 86: 2748-2757. [Abstract] [Full Text] [PDF] [Supplemental Material]  

Jesse D. Bloom, Claus O. Wilke, Frances H. Arnold, and Christoph Adami

Stability and the Evolvability of Function in a Model Protein
Biophys. J. 2004 86: 2758-2764. [Abstract] [Full Text] [PDF]  

Luca Maragliano, Grazia Cottone, Lorenzo Cordone, and Giovanni Ciccotti

Atomic Mean-Square Displacements in Proteins by Molecular Dynamics: A Case for Analysis of Variance
Biophys. J. 2004 86: 2765-2772. [Abstract] [Full Text] [PDF]  

Vitor H. Teixeira, António M. Baptista, and Cláudio M. Soares

Modeling Electron Transfer Thermodynamics in Protein Complexes: Interaction between Two Cytochromes c₃
Biophys. J. 2004 86: 2773-2785. [Abstract] [Full Text] [PDF]  

Paul Smolen, Paul E. Hardin, Brian S. Lo, Douglas A. Baxter, and John H. Byrne

Simulation of Drosophila Circadian Oscillations, Mutations, and Light Responses by a Model with VRI, PDP-1, and CLK
Biophys. J. 2004 86: 2786-2802. [Abstract] [Full Text] [PDF]  

G. Kreth, J. Finsterle, J. von Hase, M. Cremer, and C. Cremer

Radial Arrangement of Chromosome Territories in Human Cell Nuclei: A Computer Model Approach Based on Gene Density Indicates a Probabilistic Global Positioning Code
Biophys. J. 2004 86: 2803-2812. [Abstract] [Full Text] [PDF]  

Kyle C. Smith, John C. Neu, and Wanda Krassowska

Model of Creation and Evolution of Stable Electropores for DNA Delivery
Biophys. J. 2004 86: 2813-2826. [Abstract] [Full Text] [PDF]  

Tom Chou

Water Alignment, Dipolar Interactions, and Multiple Proton Occupancy during Water-Wire Proton Transport
Biophys. J. 2004 86: 2827-2836. [Abstract] [Full Text] [PDF]  

CHANNELS, RECEPTORS, AND TRANSPORTERS:

Y. Mo, T.A. Cross, and W. Nerdal

Structural Restraints and Heterogeneous Orientation of the Gramicidin A Channel Closed State in Lipid Bilayers
Biophys. J. 2004 86: 2837-2845. [Abstract] [Full Text] [PDF]  

Chien-Sung Chiang, Andriy Anishkin, and Sergei Sukharev

Gating of the Large Mechanosensitive Channel In Situ: Estimation of the Spatial Scale of the Transition from Channel Population Responses
Biophys. J. 2004 86: 2846-2861. [Abstract] [Full Text] [PDF]  

Gal Levin and Paul Blount

Cysteine Scanning of MscL Transmembrane Domains Reveals Residues Critical for Mechanosensitive Channel Gating
Biophys. J. 2004 86: 2862-2870. [Abstract] [Full Text] [PDF]  

Tal Soo Ha, Moon-Sun Heo, and Chul-Seung Park

Functional Effects of Auxiliary ß4-Subunit on Rat Large-Conductance Ca²⁺-Activated K⁺ Channel
Biophys. J. 2004 86: 2871-2882. [Abstract] [Full Text] [PDF]  

Andriy Anishkin and Sergei Sukharev

Water Dynamics and Dewetting Transitions in the Small Mechanosensitive Channel MscS
Biophys. J. 2004 86: 2883-2895. [Abstract] [Full Text] [PDF]  

MEMBRANES:

G. George Capps, Samuel Pine, Michael Edidin, and Martha C. Zúñiga

Short Class I Major Histocompatibility Complex Cytoplasmic Tails Differing in Charge Detect Arbiters of Lateral Diffusion in the Plasma Membrane
Biophys. J. 2004 86: 2896-2909. [Abstract] [Full Text] [PDF]  

S. L. Veatch, I. V. Polozov, K. Gawrisch, and S. L. Keller

Liquid Domains in Vesicles Investigated by NMR and Fluorescence Microscopy
Biophys. J. 2004 86: 2910-2922. [Abstract] [Full Text] [PDF]  

Arpita Upadhyaya and Michael P. Sheetz

Tension in Tubulovesicular Networks of Golgi and Endoplasmic Reticulum Membranes
Biophys. J. 2004 86: 2923-2928. [Abstract] [Full Text] [PDF]  

Andrey S. Klymchenko, Guy Duportail, Alexander P. Demchenko, and Yves Mély

Bimodal Distribution and Fluorescence Response of Environment-Sensitive Probes in Lipid Bilayers
Biophys. J. 2004 86: 2929-2941. [Abstract] [Full Text] [PDF]  

Benjamin L. Stottrup, Sarah L. Veatch, and Sarah L. Keller

Nonequilibrium Behavior in Supported Lipid Membranes Containing Cholesterol
Biophys. J. 2004 86: 2942-2950. [Abstract] [Full Text] [PDF]  

Vladimir S. Malinin and Barry R. Lentz

Energetics of Vesicle Fusion Intermediates: Comparison of Calculations with Observed Effects of Osmotic and Curvature Stresses
Biophys. J. 2004 86: 2951-2964. [Abstract] [Full Text] [PDF]  

Jonathan M. Crane and Lukas K. Tamm

Role of Cholesterol in the Formation and Nature of Lipid Rafts in Planar and Spherical Model Membranes
Biophys. J. 2004 86: 2965-2979. [Abstract] [Full Text] [PDF]  

Duane A. Redfern and Arne Gericke

Domain Formation in Phosphatidylinositol Monophosphate/Phosphatidylcholine Mixed Vesicles
Biophys. J. 2004 86: 2980-2992. [Abstract] [Full Text] [PDF]  

MUSCLE AND CONTRACTILITY:

Sameer B. Shah, Jennifer Davis, Noah Weisleder, Ioanna Kostavassili, Andrew D. McCulloch, Evelyn Ralston, Yassemi Capetanaki, and Richard L. Lieber

Structural and Functional Roles of Desmin in Mouse Skeletal Muscle during Passive Deformation
Biophys. J. 2004 86: 2993-3008. [Abstract] [Full Text] [PDF]  

Richard T. Tregear, Mary C. Reedy, Yale E. Goldman, Kenneth A. Taylor, Hanspeter Winkler, Clara Franzini-Armstrong, Hiroyuki Sasaki, Carmen Lucaveche, and Michael K. Reedy

Cross-Bridge Number, Position, and Angle in Target Zones of Cryofixed Isometrically Active Insect Flight Muscle
Biophys. J. 2004 86: 3009-3019. [Abstract] [Full Text] [PDF] [Supplemental Material]  

Yu. S. Borovikov, I. V. Dedova, C. G. dos Remedios, N. N. Vikhoreva, P. G. Vikhorev, S. V. Avrova, T. L. Hazlett, and B. W. Van Der Meer

Fluorescence Depolarization of Actin Filaments in Reconstructed Myofibers: The Effect of S1 or pPDM-S1 on Movements of Distinct Areas of Actin
Biophys. J. 2004 86: 3020-3029. [Abstract] [Full Text] [PDF]  

Bruce A. J. Baumann, Hua Liang, Ken Sale, Brett D. Hambly, and Piotr G. Fajer

Myosin Regulatory Domain Orientation in Skeletal Muscle Fibers: Application of Novel Electron Paramagnetic Resonance Spectral Decomposition and Molecular Modeling Methods
Biophys. J. 2004 86: 3030-3041. [Abstract] [Full Text] [PDF]  

José M. Eltit, Jorge Hidalgo, José L. Liberona, and Enrique Jaimovich

Slow Calcium Signals after Tetanic Electrical Stimulation in Skeletal Myotubes
Biophys. J. 2004 86: 3042-3051. [Abstract] [Full Text] [PDF]  

NUCLEIC ACIDS:

B. Banerjee, S. Balasubramanian, G. Ananthakrishna, T. V. Ramakrishnan, and G. V. Shivashankar

Tracking Operator State Fluctuations in Gene Expression in Single Cells
Biophys. J. 2004 86: 3052-3059. [Abstract] [Full Text] [PDF] [Supplemental Material]  

Marcelo Nöllmann, W. Marshall Stark, and Olwyn Byron

Low-Resolution Reconstruction of a Synthetic DNA Holliday Junction
Biophys. J. 2004 86: 3060-3069. [Abstract] [Full Text] [PDF] [Supplemental Material]  

Ayome Abibi, Ekaterina Protozanova, Vadim V. Demidov, and Maxim D. Frank-Kamenetskii

Specific versus Nonspecific Binding of Cationic PNAs to Duplex DNA
Biophys. J. 2004 86: 3070-3078. [Abstract] [Full Text] [PDF]  

Christopher A. Sucato, David P. Rangel, Dan Aspleaf, Bryant S. Fujimoto, and J. Michael Schurr

Monte Carlo Simulations of Locally Melted Supercoiled DNAs in 20 mM Ionic Strength
Biophys. J. 2004 86: 3079-3096. [Abstract] [Full Text] [PDF]  

PHOTOBIOPHYSICS:

Yanli Wang, Lisong Mao, and Xiche Hu

Insight into the Structural Role of Carotenoids in the Photosystem I: A Quantum Chemical Analysis
Biophys. J. 2004 86: 3097-3111. [Abstract] [Full Text] [PDF]  

Yukako Ikeura, Kazumi Shimono, Masayuki Iwamoto, Yuki Sudo, and Naoki Kamo

Role of Arg-72 of pharaonis Phoborhodopsin (Sensory Rhodopsin II) on its Photochemistry
Biophys. J. 2004 86: 3112-3120. [Abstract] [Full Text] [PDF]  

Naranbaatar Dashdorj, Wu Xu, Peter Martinsson, Parag R. Chitnis, and Sergei Savikhin

Electrochromic Shift of Chlorophyll Absorption in Photosystem I from Synechocystis sp. PCC 6803: A Probe of Optical and Dielectric Properties around the Secondary Electron Acceptor
Biophys. J. 2004 86: 3121-3130. [Abstract] [Full Text] [PDF]  

Satoru Yamaguchi, Kazumi Shimono, Yuki Sudo, Satoru Tuzi, Akira Naito, Naoki Kamo, and Hazime Saitô

Conformation and Dynamics of the [3-¹³C]Ala, [1-¹³C]Val-Labeled Truncated pharaonis Transducer, pHtrII(1–159), as Revealed by Site-Directed ¹³C Solid-State NMR: Changes Due to Association with Phoborhodopsin (Sensory Rhodopsin II)
Biophys. J. 2004 86: 3131-3140. [Abstract] [Full Text] [PDF]  

PROTEINS:

Marcelo Nöllmann, Robert Gilbert, Timothy Mitchell, Michele Sferrazza, and Olwyn Byron

The Role of Cholesterol in the Activity of Pneumolysin, a Bacterial Protein Toxin
Biophys. J. 2004 86: 3141-3151. [Abstract] [Full Text] [PDF]  

F. Gabel, M. Weik, B. P. Doctor, A. Saxena, D. Fournier, L. Brochier, F. Renault, P. Masson, I. Silman, and G. Zaccai

The Influence of Solvent Composition on Global Dynamics of Human Butyrylcholinesterase Powders: A Neutron-Scattering Study
Biophys. J. 2004 86: 3152-3165. [Abstract] [Full Text] [PDF]  

J. T. Gerig

Structure and Solvation of Melittin in 1,1,1,3,3,3-Hexafluoro-2-Propanol/Water
Biophys. J. 2004 86: 3166-3175. [Abstract] [Full Text] [PDF] [Supplemental Material]  

Martin Weik, Xavier Vernede, Antoine Royant, and Dominique Bourgeois

Temperature Derivative Fluorescence Spectroscopy as a Tool to Study Dynamical Changes in Protein Crystals
Biophys. J. 2004 86: 3176-3185. [Abstract] [Full Text] [PDF]  

SUPRAMOLECULAR ASSEMBLIES:

Thomas Gutsmann, Georg E. Fantner, Johannes H. Kindt, Manuela Venturoni, Signe Danielsen, and Paul K. Hansma

Force Spectroscopy of Collagen Fibers to Investigate Their Mechanical Properties and Structural Organization
Biophys. J. 2004 86: 3186-3193. [Abstract] [Full Text] [PDF]  

Jin Ryoun Kim and Regina M. Murphy

Mechanism of Accelerated Assembly of ß-Amyloid Filaments into Fibrils by KLVFFK₆
Biophys. J. 2004 86: 3194-3203. [Abstract] [Full Text] [PDF]  

Terence C. Flynn and Jianpeng Ma

Theoretical Analysis of Twist/Bend Ratio and Mechanical Moduli of Bacterial Flagellar Hook and Filament
Biophys. J. 2004 86: 3204-3210. [Abstract] [Full Text] [PDF]  

Michael J. Sherratt, David F. Holmes, C. Adrian Shuttleworth, and Cay M. Kielty

Substrate-Dependent Morphology of Supramolecular Assemblies: Fibrillin and Type-VI Collagen Microfibrils
Biophys. J. 2004 86: 3211-3222. [Abstract] [Full Text] [PDF]  

SPECTROSCOPY, IMAGING, OTHER TECHNIQUES:

Michael L. Gostkowski, Richard Allen, Matthew L. Plenert, Eric Okerberg, Mary Jane Gordon, and Jason B. Shear

Multiphoton-Excited Serotonin Photochemistry
Biophys. J. 2004 86: 3223-3229. [Abstract] [Full Text] [PDF]  

Karin Bettinger, Alexander Prutsch, Karsten Vogtt, and Mathias Lübben

Noninvasive Auto-Photoreduction Used as a Tool for Studying Structural Changes in Heme-Copper Oxidases by FTIR Spectroscopy
Biophys. J. 2004 86: 3230-3240. [Abstract] [Full Text] [PDF]  

S. Magazù, G. Maisano, F. Migliardo, and C. Mondelli

Mean-Square Displacement Relationship in Bioprotectant Systems by Elastic Neutron Scattering
Biophys. J. 2004 86: 3241-3249. [Abstract] [Full Text] [PDF]  

Angelo Demuro and Ian Parker

Imaging the Activity and Localization of Single Voltage-Gated Ca²⁺ Channels by Total Internal Reflection Fluorescence Microscopy
Biophys. J. 2004 86: 3250-3259. [Abstract] [Full Text] [PDF] [Supplemental Material]  

CELL BIOPHYSICS:

Paul J. Canatella, Matthew M. Black, David M. Bonnichsen, Conor McKenna, and Mark R. Prausnitz

Tissue Electroporation: Quantification and Analysis of Heterogeneous Transport in Multicellular Environments
Biophys. J. 2004 86: 3260-3268. [Abstract] [Full Text] [PDF]  

Martin Stolz, Roberto Raiteri, A. U. Daniels, Mark R. VanLandingham, Werner Baschong, and Ueli Aebi

Dynamic Elastic Modulus of Porcine Articular Cartilage Determined at Two Different Levels of Tissue Organization by Indentation-Type Atomic Force Microscopy
Biophys. J. 2004 86: 3269-3283. [Abstract] [Full Text] [PDF]  

D. Biron and E. Moses

The Effect of -Actinin on the Length Distribution of F-Actin
Biophys. J. 2004 86: 3284-3290. [Abstract] [Full Text] [PDF]  

Stéphanie Sarda, David Pointu, Frédéric Pincet, and Nelly Henry

Specific Recognition of Macroscopic Objects by the Cell Surface: Evidence for a Receptor Density Threshold Revealed by Micrometric Particle Binding Characteristics
Biophys. J. 2004 86: 3291-3303. [Abstract] [Full Text] [PDF]  

Thomas M. Fischer

Shape Memory of Human Red Blood Cells
Biophys. J. 2004 86: 3304-3313. [Abstract] [Full Text] [PDF]  

Anja Geitmann, William McConnaughey, Ingeborg Lang-Pauluzzi, Vernonica E. Franklin-Tong, and Anne Mie C. Emons

Cytomechanical Properties of Papaver Pollen Tubes Are Altered after Self-Incompatibility Challenge
Biophys. J. 2004 86: 3314-3323. [Abstract] [Full Text] [PDF]  

LETTERS TO THE EDITOR:

Vladimir S. Malinin and Barry R. Lentz

On the Analysis of Elastic Deformations in Hexagonal Phases
Biophys. J. 2004 86: 3324-3328. [Full Text] [PDF]  

CORRECTIONS:

Corrections
Biophys. J. 2004 86: 3329-3331. [Full Text] [PDF]  

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