Biophysical Journal 88 5

Cover picture: Snapshots and Voronoi diagrams for the spontaneous insertion of a model pore into a lipid bilayer. The pore plunges into the membrane in a lateral orientation. During this process, some lipids, shown in orange, become attached to the hydrophilic cap of the pore and chaperone it through the hydrophobic core of the membrane (shown in yellow). The accompanying Voronoi diagrams show the area per lipid (or pore atoms) in the leaflet where insertion is occurring. The first and second shells of lipids are shaded cyan and orange, respectively. See the article by Lopez et al. on page 3083.