Cover picture: Mesoscopic modeling of chromatin. (Top) Atomistic representation of the repeating motif in an oligonucleosome and (bottom) its mesoscopic model incorporating flexible histone tails. The “flexible-tail” model reproduces well-available experiments and opens new avenues for studying the role of histone tails and its modifications in chromatin folding and regulation. See the article by Arya et al. on page 133.