Cover picture: Reconstruction of a synapse visualized by volumetric rendering and density segmentation. Top panel shows the presynaptic terminal with vesicles clustered at the active zone. The inset shows an individual plane of another docked vesicle. Bottom panel shows the densities of different membranous organelles that were extracted (segmented) and reconstructed independently. The parallel white bands represent the pre- and postsynaptic plasma membranes, respectively, and the brown layer represents the postsynaptic densities. The three orange particles associated to the active zone belong to the presynaptic web. Docked vesicles were colored red and those deeper within the terminal are blue. Other organelles include a coated pit, three coated vesicles, and a large endosome (yellow). See the article by Zampighi et al. on page 2910.