Cover picture: Conformation and arrangement of two adjacent tubulin dimers in protofilaments forming a periodic two‐dimensional sheet in aqueous solution. Vertical white lines denote the protofilaments axes. Molecular dynamics simulations are used to optimize the tubulin conformations and arrangement in protofilaments, and subsequently, employ three-dimensional molecular theory of solvation (aka 3D-RISM) to predict the hydration structure of protofilaments and the solvent-mediated effective potential between them. See article by Drabik et al. on page 394.