Cover picture: Transformation of the structure of bacterial adhesin OpcA upon removal of the crystal contacts and crystallization agents. (Left) The conformation of OpcA resolved in the crystal structure. Loops 1 (cyan) and 2 (red) form a crevice that was proposed to harbor a binding site for proteoglycan receptors of host cells. Zinc ions (orange), which were required for protein crystallization, are shown as vdW spheres. (Right) The conformation of OpcA in a lipid bilayer membrane obtained from a 16-ns molecular dynamics simulation carried out in the absence of the zinc ions and crystal contacts. The crevice between loops 1 and 2 is no longer evident. See article by Luan et al. on page 3058.